Ontology highlight
ABSTRACT:
SUBMITTER: Petrov AS
PROVIDER: S-EPMC3753638 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Petrov Anton S AS Bernier Chad R CR Hershkovits Eli E Xue Yuzhen Y Waterbury Chris C CC Hsiao Chiaolong C Stepanov Victor G VG Gaucher Eric A EA Grover Martha A MA Harvey Stephen C SC Hud Nicholas V NV Wartell Roger M RM Fox George E GE Williams Loren Dean LD
Nucleic acids research 20130614 15
We present a de novo re-determination of the secondary (2°) structure and domain architecture of the 23S and 5S rRNAs, using 3D structures, determined by X-ray diffraction, as input. In the traditional 2° structure, the center of the 23S rRNA is an extended single strand, which in 3D is seen to be compact and double helical. Accurately assigning nucleotides to helices compels a revision of the 23S rRNA 2° structure. Unlike the traditional 2° structure, the revised 2° structure of the 23S rRNA sh ...[more]