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Replenishable dendrimer-nanoparticle hybrid membranes for sustained release of therapeutics.


ABSTRACT: We report a versatile hybrid membrane for sustained release therapeutic delivery systems. Chemically-directed assembly of a hybrid membrane of nanoparticles and dendrimers was integrated with a fluidic delivery device and a refillable drug reservoir, providing continuous sustained release.

SUBMITTER: Park MH 

PROVIDER: S-EPMC3754779 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature

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Replenishable dendrimer-nanoparticle hybrid membranes for sustained release of therapeutics.

Park Myoung-Hwan MH   Kim Sung Tae ST   Rana Subinoy S   Solfiell David D   Jeong Youngdo Y   Duncan Bradley B   Yan Bo B   Aksoy Büşra B   Rotello Vincent M VM  

Nanoscale 20130901 17


We report a versatile hybrid membrane for sustained release therapeutic delivery systems. Chemically-directed assembly of a hybrid membrane of nanoparticles and dendrimers was integrated with a fluidic delivery device and a refillable drug reservoir, providing continuous sustained release. ...[more]

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