Dataset Information

Ramifications of adolescent menstrual cycles ?42 days in young adults.

ABSTRACT:

Objective

To determine to what degree annual reports from ages 14 to 19 years of menstrual cycles ?42 days would be associated with increased body mass index (BMI), waist circumference, glucose, insulin, and homeostasis model assessment insulin resistance (HOMA-IR) at ages 14-25 years.

Design

Prospective 11-year follow-up from ages 14 to 25 years.

Setting

Urban-suburban schools, post-high school.

Patient(s)

A total of 370 schoolgirls.

Intervention(s)

None.

Main outcome measure(s)

BMI, waist, insulin, glucose, HOMA-IR.

Result(s)

From ages 14 to 19 years, 269 girls had 0/6 annual reports of menstrual cycles ?42 days, 74 had 1, 19 had 2, and 8 had ?3. Among these four categories, girls with ?3 annual reports had highest free T and DHEAS at age 14, highest BMI and waist at ages 14, 19, and 25, highest insulin at age 25, and highest glucose and HOMA-IR at age 24 years. The number of annual reports of menstrual cycles ?42 days was positively related to change in BMI and waist and inversely with change in high-density lipoprotein cholesterol from ages 14 to 25 years.

Conclusion(s)

Three or more annual reports of menstrual cycles ?42 days during ages 14-19 are associated with high BMI, waist circumference, insulin, glucose, and HOMA-IR at ages 14-25 years.

SUBMITTER: Morrison JA

PROVIDER: S-EPMC3758878 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Ramifications of adolescent menstrual cycles ≥42 days in young adults.

Morrison John A JA Glueck Charles J CJ Daniels Stephen S Wang Ping P Stroop Davis D

Fertility and sterility 20110507 1

<h4>Objective</h4>To determine to what degree annual reports from ages 14 to 19 years of menstrual cycles ≥42 days would be associated with increased body mass index (BMI), waist circumference, glucose, insulin, and homeostasis model assessment insulin resistance (HOMA-IR) at ages 14-25 years.<h4>Design</h4>Prospective 11-year follow-up from ages 14 to 25 years.<h4>Setting</h4>Urban-suburban schools, post-high school.<h4>Patient(s)</h4>A total of 370 schoolgirls.<h4>Intervention(s)</h4>None.<h4> ...[more]

PMID: 21550045

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