Ramifications of adolescent menstrual cycles ≥42 days in young adults.
Ontology highlight
ABSTRACT: Objective
To determine to what degree annual reports from ages 14 to 19 years of menstrual cycles ≥42 days would be associated with increased body mass index (BMI), waist circumference, glucose, insulin, and homeostasis model assessment insulin resistance (HOMA-IR) at ages 14-25 years.Design
Prospective 11-year follow-up from ages 14 to 25 years.Setting
Urban-suburban schools, post-high school.Patient(s)
A total of 370 schoolgirls.Intervention(s)
None.Main outcome measure(s)
BMI, waist, insulin, glucose, HOMA-IR.Result(s)
From ages 14 to 19 years, 269 girls had 0/6 annual reports of menstrual cycles ≥42 days, 74 had 1, 19 had 2, and 8 had ≥3. Among these four categories, girls with ≥3 annual reports had highest free T and DHEAS at age 14, highest BMI and waist at ages 14, 19, and 25, highest insulin at age 25, and highest glucose and HOMA-IR at age 24 years. The number of annual reports of menstrual cycles ≥42 days was positively related to change in BMI and waist and inversely with change in high-density lipoprotein cholesterol from ages 14 to 25 years.Conclusion(s)
Three or more annual reports of menstrual cycles ≥42 days during ages 14-19 are associated with high BMI, waist circumference, insulin, glucose, and HOMA-IR at ages 14-25 years.
SUBMITTER: Morrison JA
PROVIDER: S-EPMC3758878 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Publications
Ramifications of adolescent menstrual cycles ≥42 days in young adults.
Morrison John A JA Glueck Charles J CJ Daniels Stephen S Wang Ping P Stroop Davis D
Fertility and sterility 20110507 1
<h4>Objective</h4>To determine to what degree annual reports from ages 14 to 19 years of menstrual cycles ≥42 days would be associated with increased body mass index (BMI), waist circumference, glucose, insulin, and homeostasis model assessment insulin resistance (HOMA-IR) at ages 14-25 years.<h4>Design</h4>Prospective 11-year follow-up from ages 14 to 25 years.<h4>Setting</h4>Urban-suburban schools, post-high school.<h4>Patient(s)</h4>A total of 370 schoolgirls.<h4>Intervention(s)</h4>None.<h4> ...[more]
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