Ontology highlight
ABSTRACT:
SUBMITTER: Cressey TR
PROVIDER: S-EPMC3769674 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Cressey Tim R TR Best Brookie M BM Achalapong Jullapong J Stek Alice A Wang Jiajia J Chotivanich Nantasak N Yuthavisuthi Prapap P Suriyachai Pornnapa P Prommas Sinart S Shapiro David E DE Watts D Heather DH Smith Elizabeth E Capparelli Edmund E Kreitchmann Regis R Mirochnick Mark M
British journal of clinical pharmacology 20130901 3
<h4>Aim</h4>To describe the pharmacokinetics and safety of indinavir boosted with ritonavir (IDV/r) during the second and third trimesters of pregnancy and in the post-partum period.<h4>Methods</h4>IMPAACT P1026s is an on-going, prospective, non-blinded study of antiretroviral pharmacokinetics (PK) in HIV-infected pregnant women with a Thai cohort receiving IDV/r 400/100 mg twice daily during pregnancy through to 6-12 weeks post-partum as part of clinical care. Steady-state PK profiles were perf ...[more]