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ABSTRACT:
SUBMITTER: van Dongen J
PROVIDER: S-EPMC3770104 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
van Dongen Jenny J Willemsen Gonneke G Chen Wei-Min WM de Geus Eco J C EJ Boomsma Dorret I DI
Journal of lipid research 20130805 10
Heritability estimates of metabolic syndrome traits vary widely across studies. Some studies have suggested that the contribution of genes may vary with age or sex. We estimated the heritability of 11 metabolic syndrome-related traits and height as a function of age and sex in a large population-based sample of twin families (N = 2,792-27,021, for different traits). A moderate-to-high heritability was found for all traits [from H(2) = 0.47 (insulin) to H(2) = 0.78 (BMI)]. The broad-sense heritab ...[more]