Ontology highlight
ABSTRACT:
SUBMITTER: Ridge PG
PROVIDER: S-EPMC3770576 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Ridge Perry G PG Koop Andre A Maxwell Taylor J TJ Bailey Matthew H MH Swerdlow Russell H RH Kauwe John S K JS Honea Robyn A RA
PloS one 20130911 9
Various studies have suggested that the mitochondrial genome plays a role in late-onset Alzheimer's disease, although results are mixed. We used an endophenotype-based approach to further characterize mitochondrial genetic variation and its relationship to risk markers for Alzheimer's disease. We analyzed longitudinal data from non-demented, mild cognitive impairment, and late-onset Alzheimer's disease participants in the Alzheimer's Disease Neuroimaging Initiative with genetic, brain imaging, a ...[more]