Ontology highlight
ABSTRACT:
SUBMITTER: Petrovic D
PROVIDER: S-EPMC3771247 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
BioMed research international 20130827
Several candidate genes have been so far implicated in the pathogenesis of proliferative diabetic retinopathy (PDR) in subjects with type 2 diabetes. Since the principal pathogenetic mechanisms for diabetic retinopathy (DR) and PDR are different, the main pathogenetic mechanism in DR is increased vascular permeability, whereas in PDR the crucial pathogenetic mechanisms are fibrosis and neoangiogenesis. Due to that fact, different candidate genes are expected to be involved in the development of ...[more]