Ontology highlight
ABSTRACT:
SUBMITTER: Herz J
PROVIDER: S-EPMC3771356 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 20120801 4
The immune system is highly evolved and can respond to infection throughout the body. Pathogenspecific immune cells are usually generated in secondary lymphoid tissues (e.g., spleen, lymph nodes) and then migrate to sites of infection where their functionality is shaped by the local milieu. Because immune cells are so heavily influenced by the infected tissue in which they reside, it is important that their interactions and dynamics be studied in vivo. Two-photon microscopy is a powerful approac ...[more]