Ontology highlight
ABSTRACT:
SUBMITTER: Zurbuchen MA
PROVIDER: S-EPMC3773618 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Zurbuchen Mark A MA Lake Michael P MP Kohan Sirus A SA Leung Belinda B Bouchard Louis-S LS
Scientific reports 20130101
There is a growing need for biolabels that can be used in both optical and electron microscopies, are non-cytotoxic, and do not photobleach. Such biolabels could enable targeted nanoscale imaging of sub-cellular structures, and help to establish correlations between conjugation-delivered biomolecules and function. Here we demonstrate a sub-cellular multi-modal imaging methodology that enables localization of inert particulate probes, consisting of nanodiamonds having fluorescent nitrogen-vacancy ...[more]