Ontology highlight
ABSTRACT:
SUBMITTER: Gomez-Arroyo J
PROVIDER: S-EPMC3774477 | biostudies-literature | 2012 May
REPOSITORIES: biostudies-literature
American journal of physiology. Lung cellular and molecular physiology 20120203 10
Many chronic pulmonary diseases are associated with pulmonary hypertension (PH) and pulmonary vascular remodeling, which is a term that continues to be used to describe a wide spectrum of vascular abnormalities. Pulmonary vascular structural changes frequently increase pulmonary vascular resistance, causing PH and right heart failure. Although rat models had been standard models of PH research, in more recent years the availability of genetically engineered mice has made this species attractive ...[more]