Identification of LTR-specific small non-coding RNA in FeLV infected cells.
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ABSTRACT:
SUBMITTER: Forman LW
PROVIDER: S-EPMC3774839 | biostudies-literature | 2009 Apr
REPOSITORIES: biostudies-literature
Publications
Identification of LTR-specific small non-coding RNA in FeLV infected cells.
Forman Lora W LW Pal-Ghosh Ruma R Spanjaard Remco A RA Faller Douglas V DV Ghosh Sajal K SK
FEBS letters 20090329 8
The U3-LTR region of leukemia viruses transactivates cancer-related signaling pathways through the production of a non-coding RNA transcript although the role of this transcript in virus infection remains unknown. In this study we demonstrate for the first time that an long terminal repeat (LTR)-specific small non-coding RNA is produced from a feline leukemia virus (FeLV)-infected feline cell line. RNA cloning identified this as a 104 base transcript that originates from the U3-LTR region. We al ...[more]
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