Proteomic and gene expression patterns of keratoconus.
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ABSTRACT:
SUBMITTER: Ghosh A
PROVIDER: S-EPMC3775070 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Publications
Proteomic and gene expression patterns of keratoconus.
Ghosh Arkasubhra A Zhou Lei L Ghosh Anuprita A Shetty Rohit R Beuerman Roger R
Indian journal of ophthalmology 20130801 8
Keratoconus is a progressive corneal thinning disease associated with significant tissue remodeling activities and activation of a variety of signaling networks. However, it is not understood how differential gene and protein expression direct function in keratoconus corneas to drive the underlying pathology, ectasia. Research in the field has focused on discovering differentially expressed genes and proteins and quantifying their levels and activities in keratoconus patient samples. In this stu ...[more]
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