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Ligand-controlled palladium-catalyzed regiodivergent Suzuki-Miyaura cross-coupling of allylboronates and aryl halides.

ABSTRACT: An orthogonal set of catalyst systems has been developed for the Suzuki-Miyaura coupling of 3,3-disubstituted and 3-monosubstituted allylboronates with (hetero)aryl halides. These methods allow for the highly selective preparation of either the ?- or the ?-isomeric coupling product.

SUBMITTER: Yang Y

PROVIDER: S-EPMC3776608 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature

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Ligand-controlled palladium-catalyzed regiodivergent Suzuki-Miyaura cross-coupling of allylboronates and aryl halides.

Yang Yang Y Buchwald Stephen L SL

Journal of the American Chemical Society 20130712 29

An orthogonal set of catalyst systems has been developed for the Suzuki-Miyaura coupling of 3,3-disubstituted and 3-monosubstituted allylboronates with (hetero)aryl halides. These methods allow for the highly selective preparation of either the α- or the γ-isomeric coupling product. ...[more]

PMID: 23837686

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