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Cobalt-Catalyzed Suzuki Biaryl Coupling of Aryl Halides.

ABSTRACT: Readily accessed cobalt pre-catalysts with N-heterocyclic carbene ligands catalyze the Suzuki cross-coupling of aryl chlorides and bromides with alkyllithium-activated arylboronic pinacolate esters. Preliminary mechanistic studies indicate that the cobalt species is reduced to Co⁰ during the reaction.

SUBMITTER: Asghar S

PROVIDER: S-EPMC5767760 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature

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Cobalt-Catalyzed Suzuki Biaryl Coupling of Aryl Halides.

Asghar Soneela S Tailor Sanita B SB Elorriaga David D Bedford Robin B RB

Angewandte Chemie (International ed. in English) 20171128 51

Readily accessed cobalt pre-catalysts with N-heterocyclic carbene ligands catalyze the Suzuki cross-coupling of aryl chlorides and bromides with alkyllithium-activated arylboronic pinacolate esters. Preliminary mechanistic studies indicate that the cobalt species is reduced to Co<sup>0</sup> during the reaction. ...[more]

PMID: 29135071

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