Enantioselective synthesis of planar chiral ferrocenes via palladium-catalyzed annulation with diarylethynes.

ABSTRACT: When Boc-L-Val-OH was used as a ligand for the enantioselective Pd(II)-catalyzed annulation of N,N-substituted aminomethyl ferrocene derivatives with diarylethynes, ferrocenes with planar chirality could be achieved with excellent enantioselectivity (up to 99% ee).

SUBMITTER: Shi YC 

PROVIDER: S-EPMC3778326 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature