Ontology highlight
ABSTRACT:
SUBMITTER: Chang SL
PROVIDER: S-EPMC3779184 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Chang Sunny Li-Yun SL Chou Ruey-Hwang RH Zeng Hong-Jie HJ Lin Yu-Hsuan YH Chiu Tai-Yu TY Yang De-Ming DM Hung Shih-Chieh SC Lai Chih-Ho CH Hsieh Jer-Tsong JT Shyu Woei-Cherng WC Yu Yung-Luen YL
PloS one 20130920 9
The DOC-2/DAB2 interactive protein (DAB2IP) is a new member of the Ras GTPase-activating protein family. Recent studies have shown that, in addition to its tumor suppressive role in various tumors, DAB2IP also plays an important role in regulating neuronal migration and positioning during brain development. In this study, we determined the roles of DAB2IP in the neuronal differentiation of human mesenchymal stem cells (hMSCs). We found that lentiviral short hairpin RNA (shRNA)-mediated knockdown ...[more]