Ontology highlight
ABSTRACT:
SUBMITTER: Narlikar GJ
PROVIDER: S-EPMC3781322 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Narlikar Geeta J GJ Sundaramoorthy Ramasubramanian R Owen-Hughes Tom T
Cell 20130801 3
Chromatin provides both a means to accommodate a large amount of genetic material in a small space and a means to package the same genetic material in different chromatin states. Transitions between chromatin states are enabled by chromatin-remodeling ATPases, which catalyze a diverse range of structural transformations. Biochemical evidence over the last two decades suggests that chromatin-remodeling activities may have emerged by adaptation of ancient DNA translocases to respond to specific fe ...[more]