Ontology highlight
ABSTRACT:
SUBMITTER: Nelson LJ
PROVIDER: S-EPMC3781401 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Nelson Leonard J LJ Treskes Philipp P Howie A Forbes AF Walker Simon W SW Hayes Peter C PC Plevris John N JN
Scientific reports 20130101
The characterization of fully-defined in vitro hepatic culture systems requires testing of functional and morphological variables to obtain the optimal trophic support, particularly for cell therapeutics including bioartificial liver systems (BALs). Using serum-free fully-defined culture medium formulations, we measured synthetic, detoxification and metabolic variables of primary porcine hepatocytes (PPHs)--integrated these datasets using a defined scoring system and correlated this hepatocyte b ...[more]