Ontology highlight
ABSTRACT:
SUBMITTER: Barua B
PROVIDER: S-EPMC3782539 | biostudies-literature | 2013 May-Jun
REPOSITORIES: biostudies-literature
Bioarchitecture 20130501 3
Tropomyosin is an actin binding protein that regulates actin filament dynamics and its interactions with actin binding proteins such as myosin, tropomodulin, formin, Arp2/3 and ADF-cofilin in most eukaryotic cells. Tropomyosin is the prototypical two-chained, α-helical coiled coil protein that associates end-to-end and binds to both sides of the actin filament. Each tropomyosin molecule spans four to seven actin monomers in the filament, depending on the size of the tropomyosin. Tropomyosins hav ...[more]