Long-term dynamics of CA1 hippocampal place codes.
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ABSTRACT:
SUBMITTER: Ziv Y
PROVIDER: S-EPMC3784308 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Publications
Long-term dynamics of CA1 hippocampal place codes.
Ziv Yaniv Y Burns Laurie D LD Cocker Eric D ED Hamel Elizabeth O EO Ghosh Kunal K KK Kitch Lacey J LJ El Gamal Abbas A Schnitzer Mark J MJ
Nature neuroscience 20130210 3
Using Ca(2+) imaging in freely behaving mice that repeatedly explored a familiar environment, we tracked thousands of CA1 pyramidal cells' place fields over weeks. Place coding was dynamic, as each day the ensemble representation of this environment involved a unique subset of cells. However, cells in the ∼15-25% overlap between any two of these subsets retained the same place fields, which sufficed to preserve an accurate spatial representation across weeks. ...[more]
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