Ontology highlight
ABSTRACT:
SUBMITTER: Ding HM
PROVIDER: S-EPMC3786291 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Scientific reports 20130930
The major challenge in cancer therapy is to efficiently translocate drug molecules into cancer tumors without doing any damage to healthy tissues. Since there exist pH gradients between tumor and normal tissues, pH-sensitive materials may have great potential to overcome such challenge. Here, we report one new type of pH-responsive drug delivery system where pH-sensitive polymers are introduced to control the cellular uptake of nanoparticles under different pH environments through dissipative pa ...[more]