Ontology highlight
ABSTRACT:
SUBMITTER: Mousavi K
PROVIDER: S-EPMC3786356 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Molecular cell 20130829 5
Transcription factors and DNA regulatory binding motifs are fundamental components of the gene regulatory network. Here, by using genome-wide binding profiling, we show extensive occupancy of transcription factors of myogenesis (MyoD and Myogenin) at extragenic enhancer regions coinciding with RNA synthesis (i.e., eRNA). In particular, multiple regions were transcribed to eRNA within the regulatory region of MYOD1, including previously characterized distal regulatory regions (DRR) and core enhan ...[more]