Ontology highlight
ABSTRACT:
SUBMITTER: Schuetz JM
PROVIDER: S-EPMC3787098 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Schuetz Johanna M JM Daley Denise D Leach Stephen S Conde Lucia L Berry Brian R BR Gallagher Richard P RP Connors Joseph M JM Gascoyne Randy D RD Bracci Paige M PM Skibola Christine F CF Spinelli John J JJ Brooks-Wilson Angela R AR
PloS one 20130930 9
Non-Hodgkin lymphomas (NHL) are a heterogeneous group of solid tumours of lymphoid cell origin. Three important aspects of lymphocyte development include immunity and inflammation, DNA repair, and programmed cell death. We have used a previously established case-control study of NHL to ask whether genetic variation in genes involved in these three important processes influences risk of this cancer. 118 genes in these three categories were tagged with single nucleotide polymorphisms (SNPs), which ...[more]