Ontology highlight
ABSTRACT:
SUBMITTER: de-la-Re-Vega E
PROVIDER: S-EPMC3787728 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
de-la-Re-Vega Enrique E Muhlia-Almazan Adriana A Arvizu-Flores Aldo A AA Islas-Osuna Maria A MA Yepiz-Plascencia Gloria G Brieba Luis G LG Sotelo-Mundo Rogerio R RR
Results in immunology 20110726 1
Proliferating cell nuclear antigen (PCNA) is the eukaryotic sliding clamp that tethers DNA polymerase to DNA during replication. The full-length cDNA of the Pacific white shrimp Litopenaeus vannamei PCNA (LvPCNA) was cloned and encoded a protein of 260 amino acids that is highly similar to other Crustacean PCNAs. The theoretical shrimp PCNA structure has all the domains that are necessary for its interaction with template DNA and DNA polymerase. RT-PCR analysis showed that LvPCNA is expressed ma ...[more]