Ontology highlight
ABSTRACT:
SUBMITTER: Wu Y
PROVIDER: S-EPMC7112065 | biostudies-literature | 2007 Oct
REPOSITORIES: biostudies-literature
Wu Yue Y Lü Ling L Yang Li-Shi LS Weng Shao-Ping SP Chan Sui-Ming SM He Jian-Guo JG
Aquaculture (Amsterdam, Netherlands) 20070704 1
RNA interference (RNAi) is a sequence-specific, post-transcriptional process of mRNA degradation. Here, we described specific silencing of five white spot syndrome virus (WSSV) genes in <i>Litopenaeus vannamei in vivo</i> with sequence-specific siRNAs. These genes included DNA polymerase (<i>dnapol</i>), ribonucleotide reductase small subunit (<i>rr2</i>), thymidine kinase and thymidylate kinase (<i>tk-tmk</i>), <i>vp24</i> and <i>vp28</i>. At 6 days post-challenged, the relative survival rates ...[more]