Ontology highlight
ABSTRACT:
SUBMITTER: Boutet S
PROVIDER: S-EPMC3788707 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Science (New York, N.Y.) 20120531 6092
Structure determination of proteins and other macromolecules has historically required the growth of high-quality crystals sufficiently large to diffract x-rays efficiently while withstanding radiation damage. We applied serial femtosecond crystallography (SFX) using an x-ray free-electron laser (XFEL) to obtain high-resolution structural information from microcrystals (less than 1 micrometer by 1 micrometer by 3 micrometers) of the well-characterized model protein lysozyme. The agreement with s ...[more]