Different thermodynamic signatures for DNA minor groove binding with changes in salt concentration and temperature.
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ABSTRACT:
SUBMITTER: Wang S
PROVIDER: S-EPMC3791883 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
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Different thermodynamic signatures for DNA minor groove binding with changes in salt concentration and temperature.
Wang Shuo S Kumar Arvind A Aston Karl K Nguyen Binh B Bashkin James K JK Boykin David W DW Wilson W David WD
Chemical communications (Cambridge, England) 20131001 76
The effects of salt concentration and temperature on the thermodynamics of DNA minor groove binding have quite different signatures: binding enthalpy is salt concentration independent but temperature dependent. Conversely, binding free energy is salt dependent but essentially temperature independent through enthalpy-entropy compensation. ...[more]
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