Ontology highlight
ABSTRACT:
SUBMITTER: Ivancic MM
PROVIDER: S-EPMC3792563 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Ivancic Melanie M MM Huttlin Edward L EL Chen Xiaodi X Pleiman Jennifer K JK Irving Amy A AA Hegeman Adrian D AD Dove William F WF Sussman Michael R MR
Journal of proteome research 20130808 9
Current screening procedures for colorectal cancer are imperfect and highly invasive and result in increased mortality rates due to low compliance. The goal of the experiments reported herein is to identify potential blood-based biomarkers indicative of early stage intestinal cancers using the ApcMin/+ mouse model of intestinal cancer as an experimental system. Serum proteins from tumor-bearing ApcMin/+ mice were quantitatively compared to tumor-free Apc+/+ wild-type mice via in anima metabolic ...[more]