Ontology highlight
ABSTRACT:
SUBMITTER: Magenta A
PROVIDER: S-EPMC3794730 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Magenta Alessandra A Greco Simona S Gaetano Carlo C Martelli Fabio F
International journal of molecular sciences 20130822 9
Oxidative stress has been demonstrated to play a causal role in different vascular diseases, such as hypertension, diabetic vasculopathy, hypercholesterolemia and atherosclerosis. Indeed, increased reactive oxygen species (ROS) production is known to impair endothelial and vascular smooth muscle cell functions, contributing to the development of cardiovascular diseases. MicroRNAs (miRNAs) are non-coding RNA molecules that modulate the stability and/or the translational efficiency of target messe ...[more]