Cutaneous human papillomavirus 88: remarkable differences in viral load.
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ABSTRACT:
SUBMITTER: Kullander J
PROVIDER: S-EPMC3795386 | biostudies-literature | 2008 Jan
REPOSITORIES: biostudies-literature
Publications
Cutaneous human papillomavirus 88: remarkable differences in viral load.
Kullander Johanna J Handisurya Alessandra A Forslund Ola O Geusau Alexandra A Kirnbauer Reinhard R Dillner Joakim J
International journal of cancer 20080101 2
A human papillomavirus (HPV) was cloned from a patient with multiple squamous cell carcinomas (SCCs) and identified as HPV88, recently categorized into a new species within the genus Gamma. The HPV88 viral load in an SCC of the index patient exceeded 1 million copies/cell. By contrast, a survey of 447 skin lesions (79 actinic keratoses, 73 seborrhoeic keratoses, 169 basal cell carcinomas and 126 SCCs) and 362 healthy skin biopsies found detectable HPV88 DNA in only 7 specimens. All these had ver ...[more]
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