Ontology highlight
ABSTRACT:
SUBMITTER: Hirose M
PROVIDER: S-EPMC3795557 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Hirose Mika M Sugiyama Shigeru S Ishida Hanako H Niiyama Mayumi M Matsuoka Daisuke D Hara Toshiaki T Mizohata Eiichi E Murakami Satoshi S Inoue Tsuyoshi T Matsuoka Shigeru S Murata Michio M
Journal of synchrotron radiation 20131001 Pt 6
Heart-type fatty-acid-binding protein (FABP3), which is a cytosolic protein abundantly found in cardiomyocytes, plays a role in trafficking fatty acids throughout cellular compartments by reversibly binding intracellular fatty acids with relatively high affinity. The fluorescent probe 1-anilinonaphthalene-8-sulfonate (ANS) is extensively utilized for examining the interaction of ligands with fatty-acid-binding proteins. The X-ray structure of FABP3 was determined in the presence of ANS and revea ...[more]