Ontology highlight
ABSTRACT:
SUBMITTER: Hill SY
PROVIDER: S-EPMC3796118 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Hill Shirley Y SY Jones Bobby L BL Holmes Brian B Steinhauer Stuart R SR Zezza Nicholas N Stiffler Scott S
Psychiatry research 20130607 3
P300 amplitude in childhood predicts substance use disorders by young adulthood. Trajectories of visual P300 amplitude show an association between low amplitude P300 and familial risk for alcohol dependence (AD). Variation in the cholinergic muscarinic receptor gene (CHRM2) has previously been associated with P300 amplitude and AD. The present study used group based trajectory modeling of auditory P300 data collected longitudinally from offspring in families with and without familial loading for ...[more]