Ontology highlight
ABSTRACT:
SUBMITTER: Hook AL
PROVIDER: S-EPMC3796337 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Hook Andrew L AL Chang Chien-Yi CY Yang Jing J Luckett Jeni J Cockayne Alan A Atkinson Steve S Mei Ying Y Bayston Roger R Irvine Derek J DJ Langer Robert R Anderson Daniel G DG Williams Paul P Davies Martyn C MC Alexander Morgan R MR
Nature biotechnology 20120901 9
Bacterial attachment and subsequent biofilm formation pose key challenges to the optimal performance of medical devices. In this study, we determined the attachment of selected bacterial species to hundreds of polymeric materials in a high-throughput microarray format. Using this method, we identified a group of structurally related materials comprising ester and cyclic hydrocarbon moieties that substantially reduced the attachment of pathogenic bacteria (Pseudomonas aeruginosa, Staphylococcus a ...[more]