Dataset Information

Sex differences in the relationship between asthma and overweight in Dutch children: a survey study.

ABSTRACT:

Objective

Obesity has been identified as a risk factor for asthma in children. However, in the Netherlands, the obesity prevalence is rising while the asthma prevalence in children is stabilising. The aim of this study is to clarify the association between asthma and Body Mass Index (BMI) in children and whether this association is influenced by sex.

Study design

Parents of 39,316 children (6-16 years) in the south of the Netherlands were invited to complete an online questionnaire on respiratory symptoms, anthropometric variables and several potential confounding factors for asthma and obesity (including sex, birth weight and breastfeeding). Data was analysed by multivariable logistic regression models and an ordinal regression model.

Results

The response rate was 24% (n boys= 4,743, n girls= 4,529). The prevalence of asthma, overweight and obesity was 8%, 15% and 2% respectively. Body mass index--standard deviation Score (BMI-SDS) was related to current asthma (adjusted OR: 1.29; 95%CI: 1.14-1.45, p ? 0.001). When stratified for sex, asthma and BMI-SDS were only related in girls (Girls: adjusted OR: 1.31; 95%CI: 1.13-1.51, p ? 0.001. Boys: adjusted OR: 1.01; 95%CI: 0.91-1.14, p=0.72).

Conclusions

The positive association between BMI-SDS and asthma is only present in girls, not boys. Future studies into obesity and asthma should correct for sex in their analyses.

SUBMITTER: Willeboordse M

PROVIDER: S-EPMC3804131 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature

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Publications

Sex differences in the relationship between asthma and overweight in Dutch children: a survey study.

Willeboordse Maartje M van den Bersselaar Donna L C M DL van de Kant Kim D G KD Muris Jean W M JW van Schayck Onno C P OC Dompeling Edward E

PloS one 20131017 10

<h4>Objective</h4>Obesity has been identified as a risk factor for asthma in children. However, in the Netherlands, the obesity prevalence is rising while the asthma prevalence in children is stabilising. The aim of this study is to clarify the association between asthma and Body Mass Index (BMI) in children and whether this association is influenced by sex.<h4>Study design</h4>Parents of 39,316 children (6-16 years) in the south of the Netherlands were invited to complete an online questionnair ...[more]

PMID: 24204876

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Project description:The relationship between body weight changes in late life and cognitive function is controversial.We investigated whether weight gain or loss in late life affected cognitive function in community-dwelling older adults over a 3-year period.Our study used data from the Survey of Living Conditions and Welfare Needs of Korean Older Persons and included 3859 subjects (aged ≥65 years) with normal cognition at baseline. At baseline and the 3-year follow-up, body weight and height were measured, and cognitive function was assessed using the mini-mental state examination. Based on their body mass index (BMI) at baseline and follow-up, we divided the subjects into 4 groups: weight gain (baseline BMI <23 kg/m and follow-up BMI ≥23 kg/m); weight loss (baseline BMI ≥23 kg/m and follow-up BMI <23 kg/m); stable overweight/obese (BMI ≥23 kg/m at both visits); and stable non-overweight/obese (BMI <23 kg/m at both visits). Incidence rates (IRs) of cognitive impairment per 100 persons and IR ratios (IRRs) were calculated for each group and adjusted for confounding variables.At the 3-year follow-up, 610 cases of cognitive impairment (15.8%) were identified. The stable overweight/obese group had the lowest IR (14.0, 95% confidence interval [CI] 12.45-15.71) and was therefore used as the reference group when calculating IRRs for cognitive impairment. When men and women were evaluated separately, IRs between groups were significantly different only for women. The stable non-overweight/obese group (IRR 1.65, 95% CI 1.22-2.22) and the weight gain group (IRR 1.93, 95% CI 1.24-3.01) had higher IRs than those in the stable overweight/obese group. As a gain or loss of adiposity, the IR of the weight gain group (IRR 1.17, 95% CI 0.74-1.84) was not different from that of the stable non-overweight/obese group. Also, the IR of weight loss group (IRR 1.09, 95% CI 0.71-1.67) was not significantly different from that of the stable overweight/obese group.We suggest that overweight or obese older women at baseline had cognitive benefits. However, additional gain or loss of adiposity in late life did not affect the risk of cognitive impairment.

Dataset Information

Sex differences in the relationship between asthma and overweight in Dutch children: a survey study.

Objective

Study design

Results

Conclusions

Publications

Sex differences in the relationship between asthma and overweight in Dutch children: a survey study.

Similar Datasets

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