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Multifactorial diversity sustains microbial community stability.

ABSTRACT: Maintenance of a high degree of biodiversity in homogeneous environments is poorly understood. A complex cheese starter culture with a long history of use was characterized as a model system to study simple microbial communities. Eight distinct genetic lineages were identified, encompassing two species: Lactococcus lactis and Leuconostoc mesenteroides. The genetic lineages were found to be collections of strains with variable plasmid content and phage sensitivities. Kill-the-winner hypothesis explaining the suppression of the fittest strains by density-dependent phage predation was operational at the strain level. This prevents the eradication of entire genetic lineages from the community during propagation regimes (back-slopping), stabilizing the genetic heterogeneity in the starter culture against environmental uncertainty.

SUBMITTER: Erkus O

PROVIDER: S-EPMC3806261 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature

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Multifactorial diversity sustains microbial community stability.

Erkus Oylum O de Jager Victor C L VC Spus Maciej M van Alen-Boerrigter Ingrid J IJ van Rijswijck Irma M H IM Hazelwood Lucie L Janssen Patrick W M PW van Hijum Sacha A F T SA Kleerebezem Michiel M Smid Eddy J EJ

The ISME journal 20130704 11

Maintenance of a high degree of biodiversity in homogeneous environments is poorly understood. A complex cheese starter culture with a long history of use was characterized as a model system to study simple microbial communities. Eight distinct genetic lineages were identified, encompassing two species: Lactococcus lactis and Leuconostoc mesenteroides. The genetic lineages were found to be collections of strains with variable plasmid content and phage sensitivities. Kill-the-winner hypothesis ex ...[more]

PMID: 23823494

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