Ontology highlight
ABSTRACT:
SUBMITTER: Kettenbach AN
PROVIDER: S-EPMC3808085 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Kettenbach Arminja N AN Schweppe Devin K DK Faherty Brendan K BK Pechenick Dov D Pletnev Alexandre A AA Gerber Scott A SA
Science signaling 20110628 179
Mitosis is a process involving a complex series of events that require careful coordination. Protein phosphorylation by a small number of kinases, in particular Aurora A, Aurora B, the cyclin-dependent kinase-cyclin complex Cdk1/cyclinB, and Polo-like kinase 1 (Plk1), orchestrates almost every step of cell division, from entry into mitosis to cytokinesis. To discover more about the functions of Aurora A, Aurora B, and kinases of the Plk family, we mapped mitotic phosphorylation sites to these ki ...[more]