Ontology highlight
ABSTRACT:
SUBMITTER: Weber MD
PROVIDER: S-EPMC3810175 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Weber Michael D MD Frank Matthew G MG Sobesky Julia L JL Watkins Linda R LR Maier Steven F SF
Brain, behavior, and immunity 20130315
Acute and chronic stressors sensitize or prime the neuroinflammatory response to a subsequent peripheral or central immunologic challenge. However, the neuroimmune process(es) by which stressors prime or sensitize subsequent neuroinflammatory responses remains unclear. Prior evidence suggested that toll-like receptors (TLRs) might be involved in the mediation of primed neuroinflammatory responses, but the role of TLRs during a stressor has never been directly tested. Here, a novel TLR2 and TLR4 ...[more]