Ontology highlight
ABSTRACT:
SUBMITTER: Fuentes TI
PROVIDER: S-EPMC3810469 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Fuentes Tania I TI Appleby Nancy N Tsay Eric E Martinez J Julian JJ Bailey Leonard L Hasaniya Nahidh N Kearns-Jonker Mary M
PloS one 20131028 10
Although clinical benefit can be achieved after cardiac transplantation of adult c-kit+ or cardiosphere-derived cells for myocardial repair, these stem cells lack the regenerative capacity unique to neonatal cardiovascular stem cells. Unraveling the molecular basis for this age-related discrepancy in function could potentially transform cardiovascular stem cell transplantation. In this report, clonal populations of human neonatal and adult cardiovascular progenitor cells were isolated and charac ...[more]