Probing 3-hydroxyflavone for in vitro glycorandomization of flavonols by YjiC.
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ABSTRACT:
SUBMITTER: Pandey RP
PROVIDER: S-EPMC3811512 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Publications
Probing 3-hydroxyflavone for in vitro glycorandomization of flavonols by YjiC.
Pandey Ramesh Prasad RP Parajuli Prakash P Koirala Niranjan N Park Je Won JW Sohng Jae Kyung JK
Applied and environmental microbiology 20130823 21
The glycosylation of five different flavonols, fisetin, quercetin, myricetin, kaempferol, and 3-hydroxyflavone, was achieved by applying YjiC. 3-Hydroxyflavone was selected as a probe for in vitro glycorandomization of all flavonols using diverse nucleotide diphosphate-d/l-sugars. This study unlocked the possibilities of the glycodiversification of flavonols and the generation of novel compounds as future therapeutics. ...[more]
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