Ontology highlight
ABSTRACT:
SUBMITTER: Gao R
PROVIDER: S-EPMC3812086 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
PLoS genetics 20131024 10
Cellular adaptation relies on the development of proper regulatory schemes for accurate control of gene expression levels in response to environmental cues. Over- or under-expression can lead to diminished cell fitness due to increased costs or insufficient benefits. Positive autoregulation is a common regulatory scheme that controls protein expression levels and gives rise to essential features in diverse signaling systems, yet its roles in cell fitness are less understood. It remains largely u ...[more]