Genome-wide estimates of coancestry and inbreeding in a closed herd of ancient Iberian pigs.

ABSTRACT: Maintaining genetic variation and controlling the increase in inbreeding are crucial requirements in animal conservation programs. The most widely accepted strategy for achieving these objectives is to maximize the effective population size by minimizing the global coancestry obtained from a particular pedigree. However, for most natural or captive populations genealogical information is absent. In this situation, microsatellites have been traditionally the markers of choice to characterize genetic variation, and several estimators of genealogical coefficients have been developed using marker data, with unsatisfactory results. The development of high-throughput genotyping techniques states the necessity of reviewing the paradigm that genealogical coancestry is the best parameter for measur

SUBMITTER: Saura M 

PROVIDER: S-EPMC3814548 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature