Ontology highlight
ABSTRACT:
SUBMITTER: Mooney M
PROVIDER: S-EPMC3815469 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Mooney Michael M McWeeney Shannon S Sékaly Rafick-Pierre RP
Seminars in immunology 20130401 2
Vaccines are the most cost effective public health measure for preventing viral infection and limiting epidemic spread within susceptible populations. However, the efficacy of current protective vaccines is highly variable, particularly in aging populations. In addition, there have been a number of challenges in the development of new vaccines due to a lack of detailed understanding of the immune correlates of protection. To identify the mechanisms underlying the variability of the immune respon ...[more]