Ontology highlight
ABSTRACT:
SUBMITTER: Crusat M
PROVIDER: S-EPMC3820038 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Virology 20130917 1-2
As avian influenza A(H5N1) viruses continue to circulate in Asia and Africa, global concerns of an imminent pandemic persist. Recent experimental studies suggest that efficient transmission between humans of current H5N1 viruses only requires a few genetic changes. An essential step is alteration of the virus hemagglutinin from preferential binding to avian receptors for the recognition of human receptors present in the upper airway. We have identified receptor-binding changes which emerged duri ...[more]