Ontology highlight
ABSTRACT:
SUBMITTER: Rogers JT
PROVIDER: S-EPMC3820099 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Rogers Justin T JT Zhao Lisa L Trotter Justin H JH Rusiana Ian I Peters Melinda M MM Li Qingyou Q Donaldson Erika E Banko Jessica L JL Keenoy Kathleen E KE Rebeck G William GW Hoe Hyang-Sook HS D'Arcangelo Gabriella G Weeber Edwin J EJ
Journal of psychopharmacology (Oxford, England) 20121026 4
The lipoprotein receptor ligand Reelin is important for the processes of normal synaptic plasticity, dendritic morphogenesis, and learning and memory. Heterozygous reeler mice (HRM) show many neuroanatomical, biochemical, and behavioral features that are associated with schizophrenia. HRM show subtle morphological defects including reductions in dendritic spine density, altered synaptic plasticity and behavioral deficits in associative learning and memory and pre-pulse inhibition. The present st ...[more]