Ontology highlight
ABSTRACT:
SUBMITTER: Basu Mallick C
PROVIDER: S-EPMC3820762 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Basu Mallick Chandana C Iliescu Florin Mircea FM Möls Märt M Hill Sarah S Tamang Rakesh R Chaubey Gyaneshwer G Goto Rie R Ho Simon Y W SY Gallego Romero Irene I Crivellaro Federica F Hudjashov Georgi G Rai Niraj N Metspalu Mait M Mascie-Taylor C G Nicholas CG Pitchappan Ramasamy R Singh Lalji L Mirazon-Lahr Marta M Thangaraj Kumarasamy K Villems Richard R Kivisild Toomas T
PLoS genetics 20131107 11
Skin pigmentation is one of the most variable phenotypic traits in humans. A non-synonymous substitution (rs1426654) in the third exon of SLC24A5 accounts for lighter skin in Europeans but not in East Asians. A previous genome-wide association study carried out in a heterogeneous sample of UK immigrants of South Asian descent suggested that this gene also contributes significantly to skin pigmentation variation among South Asians. In the present study, we have quantitatively assessed skin pigmen ...[more]