Ontology highlight
ABSTRACT:
SUBMITTER: Jang KH
PROVIDER: S-EPMC3821700 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Jang Kyoung Hwa KH Nam Sang-Jip SJ Locke Jeffrey B JB Kauffman Christopher A CA Beatty Deanna S DS Paul Lauren A LA Fenical William W
Angewandte Chemie (International ed. in English) 20130617 30
Licensed to kill: A new antibiotic, anthracimycin (see scheme), produced by a marine-derived actinomycete in saline culture, shows significant activity toward Bacillus anthracis, the bacterial pathogen responsible for anthrax infections. Chlorination of anthracimycin gives a dichloro derivative that retains activity against Gram-positive bacteria, such as anthrax, but also shows activity against selected Gram-negative bacteria. ...[more]