Ontology highlight
ABSTRACT:
SUBMITTER: Low SY
PROVIDER: S-EPMC3822576 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Low Swee Yang SY Dannemiller Karen K Yao Maosheng M Yamamoto Naomichi N Peccia Jordan J
Fungal biology 20110323 7
Common indoor and outdoor environmental fungi such as Aspergillus fumigatus produce asexual spores containing a collection of proteins that can bind IgE antibodies and trigger allergic reactions. We characterized the impact of sporulation temperature on the IgE-binding capacity (allergenicity) of A. fumigatus and explored the links between variable allergenicity and temperature-dependant expression of genes encoding these allergenic proteins. A 12-fold increase in A. fumigatus allergenicity per ...[more]