Ontology highlight
ABSTRACT:
SUBMITTER: Kimura R
PROVIDER: S-EPMC3826674 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Kimura Rino R Takahashi Nobuyuki N Takahashi Nobuyuki N Lin Shan S Goto Tsuyoshi T Murota Kaeko K Nakata Rieko R Inoue Hiroyasu H Kawada Teruo T
Journal of lipid research 20131016 12
It is known that peroxisome proliferator-activated receptor (PPAR)α, whose activation reduces hyperlipidemia, is highly expressed in intestinal epithelial cells. Docosahexaenoic acid (DHA) could improve postprandial hyperlipidemia, however, its relationship with intestinal PPARα activation is not revealed. In this study, we investigated whether DHA can affect postprandial hyperlipidemia by activating intestinal PPARα using Caco-2 cells and C57BL/6 mice. The genes involved in fatty acid (FA) oxid ...[more]