Ontology highlight
ABSTRACT:
SUBMITTER: Serrano J
PROVIDER: S-EPMC3827101 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Serrano Janeth J Romo Enrique E Bermúdez Mercedes M Narayanan A Sampath AS Zeichner-David Margarita M Santos Leticia L Arzate Higinio H
PloS one 20131112 11
Gene therapy approaches to bone and periodontal tissue engineering are being widely explored. While localized delivery of osteogenic factors like BMPs is attractive for promotion of bone regeneration; method of delivery, dosage and side effects could limit this approach. A novel protein, Cementum Protein 1 (CEMP1), has recently been shown to promote regeneration of periodontal tissues. In order to address the possibility that CEMP1 can be used to regenerate other types of bone, experiments were ...[more]