Ontology highlight
ABSTRACT:
SUBMITTER: Poulin B
PROVIDER: S-EPMC3828762 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Poulin Benoit B Patzewitz Eva-Maria EM Brady Declan D Silvie Olivier O Wright Megan H MH Ferguson David J P DJ Wall Richard J RJ Whipple Sarah S Guttery David S DS Tate Edward W EW Wickstead Bill B Holder Anthony A AA Tewari Rita R
Biology open 20130916 11
The phylum Apicomplexa comprises over 5000 intracellular protozoan parasites, including Plasmodium and Toxoplasma, that are clinically important pathogens affecting humans and livestock. Malaria parasites belonging to the genus Plasmodium possess a pellicle comprised of a plasmalemma and inner membrane complex (IMC), which is implicated in parasite motility and invasion. Using live cell imaging and reverse genetics in the rodent malaria model P. berghei, we localise two unique IMC sub-compartmen ...[more]